Effect of the type of a coronary stent on dynamics of quality of life in patients with ischaemic heart disease

Sukovatykh B.S., Sukovatykh M.B., Polyansky D.V.

Kursk State Medical University of the RF Ministry of Public Health, Kursk, Russia

The purpose of the present study was to investigate the dynamics of quality of life in patients with ischaemic heart disease before and after implantation of a coronary stent depending on the stent’s type and patient’s gender.

The authors analysed the dynamics of quality of life in a total of 120 patients with ischaemic heart disease. The patients were subdivided into two equal groups of 60 each. Group One patients were subjected to implantation of bare-metal stents, whereas Group Two patients received stents coated with zotarolimus as an antiproliferative agent. The control group was composed of 60 people who did not suffer from ischaemic heart disease and were comparable by the age and gender. Quality of life was investigated prior to stent implantation and 6, 12 and 24 months thereafter with the use of the SF-36 questionnaire.

It was determined that the indices of quality of life before stenting of coronary arteries was higher in men than in women. However, no gender-related differences were revealed after stent implantation. The dynamics of the parameters of quality of life of patients following implantation of uncoated metal stents within 6 months turned out to have a positive and then rapidly progressing negative course, whereas implantation of stents coated with antiproliferative drug zotarolimus was within 12 months followed and accompanied by a positive and then slowly progressing negative course.

KEY WORDS: ischaemic heart disease, bare-metal stent, stent coated with antiproliferative drug zotarolimus, quality of life, gender-related differences.

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