Autoimmune inflammation and heterogeneity of arterial hypertension in rheumatic patients

Shilkina N.P.

Department of Propedeutics of Internal Diseases Yaroslavl State Medical Academy, Yaroslavl, Russia

The lecture presented hereinafter deals with the present-day evidence concerning interrelationships between arterial hypertension and immune inflammation in rheumatic diseases. The development of arterial hypertension, atherosclerosis, and chronic cardiac insufficiency (heart failure) in autoimmune processes is conditioned by not only classical risk factors but also by immunoinflammatory pathogenetic mechanisms of these diseases. Recently, there have appeared reports concerning the interrelationship between the activity of rheumatic diseases and the character and progression of arterial hypertension, as well as detecting elevated contents of CRP and some other cytokines, particularly tumour necrosis factor-alpha, in blood of hypertensive patients.

KEY WORDS: rheumatic diseases, arterial hypertension, activity of immune inflammation, cytokines.

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