Rosuvastatin in prevention of cardiac complications following surgical treatment of patients with vascular pathology

Pokrovsky A.V., Kuntsevich G.I., Zotikov A.E., Golovyuk A.L., Burtseva E.A., Ivanova L.O., Suntsov D.S.

Department of Vascular Surgery State Federal Facility «A.V. Vishnevsky Institute of Surgery» Moscow, Russia

The article deals with the findings of studying the use of rosuvastatin in patients after endured reconstructive operations on the brachiocephalic arteries and aortofemoral segment in order to prevent cardiac atherothrombotic complications. A total of thirty patients were given «Crestor» at a daily dose of 10 mg for two weeks prior to surgery and for two weeks postoperatively and were found to have a significant decrease in the average levels of total cholesterol and low-density lipoproteins, which was accompanied and followed by certain improvement in the functional state of the vascular wall, with no cardiac complications being observed in either case.

KEY WORDS: atherothrombosis, endothelial function, cardiac complications, vascular reconstructive operations, rosuvastatin.

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