FIRST EXPERIENCE IN USING CARDIOCYTOPROTECTOR MEXICOR IN OPERATIONS OF MYOCARDIAL REVASCULARIZATION UNDER CONDITIONS OF EXTRACORPOREAL CIRCULATION

Boyarinov G.A., Brichkin Yu.D., Bogush A.V., Melnikov N.Yu., Smorkalov A.Yu., Belonogov M.A., Pichugin V.V., Spitskaya I.V., Dudina E.V.
Federal Educational Facility «Nizhni Novgorod State Medical Academy»,
Federal Facility «Specialized Cardiosurgical clinical Hospital»,
Nizhni Novgorod, Russia

We examined a total of forty-four patients diagnosed with coronary artery disease who were subjected to coronary artery bypass graft surgery under conditions of extracorporeal circulation. In the examined group (15 patients) during anaesthesia and perfusion, we additionally administered the cardiocytoprotector mexicor at a total dose of 1,500 mg. It was revealed that administering mexicor in a complex of anaesthesiological and resuscitation support considerably increased the indices of myocardial contractility and oxygen-transporting function of blood in the postperfusion period, also decreasing both the amount and duration of inotropic stimulation, and favourably contributing to early recovery and restoration of spontaneous respiration in the immediate postoperative period.

KEY WORDS: coronary artery disease, coronary artery bypass grafting, extracorporeal circulation, mexicor.

P. 19-23

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