DRUG THERAPY OF CHRONIC VENOUSINSUFFICIENCY WITH VENZA

L.I. Bogdanetz1, V.S. Arakelian2, S.V. Sapelkin3, E.V. Kalinina
The Chair of Faculty Surgery, Faculty of Postgraduate Education,
Russian State Medical University;
A.N. Bakulev Research Center of Cardiovacular Surgery;
A.V. Vishnevsky Institute of Surgery,
Moscow, Russia

An open prospective study on the use of the drug Venza for complex variceal disease treatment was conducted. The study included 125 patients aged from 21 to 75. The outcome measures were: patient complaints and medical history, as well as Doppler ultrasound of lower limb veins, arteriovenous index (AVI) and leg circumference at the ankle level for the objective assessment of therapeutic effectiveness.Malleolar circumference decreased by average 0.8±0.3 cm. The drug therapy resulted in the regression of clinical signs (leg fatigue heaviness and edema, night palsies). Venza had a positive effect on all evaluated parameters of patient's quality of life. Its clinical effectiveness was estimated as "very good" and "good" in 27.5% and 57.5%, respectively.The study proved the Venza's effectiveness in treatment of patients with lower limb chronic venous insufficiency.

KEY WORDS: chronic venous insufficiency, drug therapy.

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