Safety and efficacy of various regimens of heparin-mediated prevention of venous thromboses in patients with intracranial haemorrhage

Khripun A.I.¹, Shuryguin S.N.², Pryamikov A.D.^1,2, Mironkov A.V.², Asratyan S.A.², Petrenko N.V.², Abashin M.V.², Latonov V.V.²

1) Chair of Surgery and Endoscopy of the Department of Advanced Medical Training of the Russian State Medical University,
2) Municipal Clinical Hospital №12, Moscow, Russia

Analysed in the article is the incidence rate of the development of venous thromboembolic complications in a total of 79 patients presenting with various-aetiology intracranial haemorrhage in different regimens of heparin-mediated prevention. The authors have revealed that early (on day 2–4 after the onset of the disease) administration of preventive doses of heparin in patients with intracerebral and intracranial haematomas is a safe and efficient regimen, since it decreases the rate of venous thromboses in the system of the vena cava inferior and fatal thromboembolic complications as compared with a later term (on day 5 and more) of initiating heparin-mediated prevention.

KEY WORDS: intracerebral and intracranial haemorrhage, heparin-mediated prevention of venous thromboembolic complications.

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