EXPERIENCE IN USING STENTS WITH AN ANTIPROLIFERATIVE COATING IN TREATMENT OF STENOSES AND OCCLUSIONS OF CORONARY ARTERIES. REVIEW OF THE LITERATURE

Krylov A.L.
Research Institute of Cardiology Tomsk Scientific Centre of the Siberian Branch of the Russian Academy of Medical Sciences,
Tomsk, Russia

The authors analysed the data concerning sirolimus- and paclitaxel-eluting stents used for treatment of stenoses and chronic occlusions of coronary arteries. Also discussed herein are clinical outcomes following stenting of bifurcation stenoses, stenoses of the main trunk of the left coronary artery, diffuse steno-ses and chronic occlusions. The authors concluded that introduction into clinical practice of stents with an antiproliferative coating made it possible to considerably improve the results of coronary angioplasty in the above-mentioned lesions of coronary arteries. At the same time, the incidence rate of restenoses, secondary revascularizations and unfavourable outcomes for drug-eluting stents in various lesions of the coronary bed remains sufficiently rather high and is 2-3 times greater than similar indices in focal stenoses.

KEY WORDS: sirolimus, paclitaxel, stenosis, chronic occlusion.

P. 81

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