Urapidil as a drug of choice for decreasing arterial pressure in surgical practice

Ilyin S.A.

Institute of Surgery named after A.V. Vishnevsky under the RF Ministry of Public Health, Moscow, Russia

Arterial hypertension as a complication of the perioperative period is encountered in 6-20% of patients undergoing general surgical interventions. This article provides a detailed discussion of epidemiology and pathophysiological aspects of arterial hypertension in surgical patients, as well as physiology and the classification of the receptor complex participating in regulation of arterial pressure. Special attention is paid to clinical trials dedicated to using Urapidil (Ebrantil^®) which belongs to the group of α₁-adrenoblockers.

KEY WORDS: arterial hypertension, Urapidil, α₁-adrenoreceptors, perioperative arterial pressure control, pheochromocytoma.

P. 158

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